Understanding Adderall: An Overview

Different forms of Adderall medication: immediate-release tablets and extended-release capsules
Adderall belongs to a class of medications called central nervous system (CNS) stimulants. When prescribed appropriately, it helps increase attention and decrease restlessness in people with ADHD by affecting certain neurotransmitters in the brain, particularly dopamine and norepinephrine. For those with narcolepsy, it helps reduce daytime sleepiness and improves wakefulness.
As a controlled substance (Schedule II), Adderall has a high potential for dependence and requires careful medical supervision. It should only be taken as prescribed by a healthcare provider, and its use should be regularly monitored to ensure safety and effectiveness.
Types of Adderall Available
Adderall comes in two primary formulations, each designed to address different treatment needs. Understanding the differences between these formulations can help patients and healthcare providers determine the most appropriate option.
Adderall IR (Immediate-Release)

Immediate-release Adderall tablets release the medication into your bloodstream right away after ingestion. Effects typically begin within 30 minutes, peak at about 3 hours, and last for 4-6 hours. This formulation is often taken 2-3 times daily to maintain consistent symptom control throughout the day.
Dosage | Color | Shape | Imprint | Description |
5mg | Blue | Round | AD 5 | Blue round tablet with “AD” and “5” imprinted |
7.5mg | Blue | Oval | AD 7.5 | Blue oval tablet with “AD” and “7.5” imprinted |
10mg | Blue | Round | AD 10 | Blue round tablet with “AD” and “10” imprinted |
12.5mg | Orange | Round | AD 12.5 | Orange round tablet with “AD” and “12.5” imprinted |
15mg | Orange | Oval | AD 15 | Orange oval tablet with “AD” and “15” imprinted |
20mg | Orange | Round | AD 20 | Orange round tablet with “AD” and “20” imprinted |
30mg | Orange | Round | AD 30 | Orange round tablet with “AD” and “30” imprinted |
Adderall XR (Extended-Release)

Extended-release Adderall capsules (Adderall XR) are designed to release the medication gradually. This formulation provides a steady level of medication throughout the day with a single morning dose. Effects typically begin within 30-60 minutes, and the therapeutic effects can last 10-12 hours, eliminating the need for multiple doses throughout the day.
Dosage | Color | Shape | Imprint | Description |
5mg | Blue/Clear | Capsule | ADDERALL XR 5mg | Blue/clear capsule with “ADDERALL XR 5mg” imprinted |
10mg | Blue/Blue | Capsule | ADDERALL XR 10mg | Blue capsule with “ADDERALL XR 10mg” imprinted |
15mg | Blue/White | Capsule | ADDERALL XR 15mg | Blue/white capsule with “ADDERALL XR 15mg” imprinted |
20mg | Orange/Orange | Capsule | ADDERALL XR 20mg | Orange capsule with “ADDERALL XR 20mg” imprinted |
25mg | Orange/White | Capsule | ADDERALL XR 25mg | Orange/white capsule with “ADDERALL XR 25mg” imprinted |
30mg | Orange/Clear | Capsule | ADDERALL XR 30mg | Orange/clear capsule with “ADDERALL XR 30mg” imprinted |
Generic vs. Brand-Name Adderall

Both Adderall IR and Adderall XR are available as brand-name medications and as generic versions (amphetamine salt combo). While the active ingredients are identical, there may be differences in the inactive ingredients, which can occasionally affect how individuals respond to the medication. Generic versions are typically more affordable and are considered bioequivalent to their brand-name counterparts by the FDA.
If you’re switching between brand-name and generic versions of Adderall, it’s important to monitor for any changes in effectiveness or side effects. Some patients report subtle differences in how they respond to different manufacturers’ versions of the medication.
Mydayis: The Newer Extended-Release Option
Mydayis is a newer medication that contains the same active ingredients as Adderall but is designed to last even longer—up to 16 hours. It’s available in 12.5mg, 25mg, 37.5mg, and 50mg capsules. Mydayis is only approved for individuals 13 years and older.
Adderall Ingredients: What’s Inside

Active Ingredients
Adderall contains a specific mixture of amphetamine salts in equal proportions (1:1:1:1 ratio):
- Amphetamine Aspartate Monohydrate – 25% of the active ingredient
- Amphetamine Sulfate – 25% of the active ingredient
- Dextroamphetamine Saccharate – 25% of the active ingredient
- Dextroamphetamine Sulfate – 25% of the active ingredient
This specific combination of amphetamine salts was designed to provide a balanced therapeutic effect. The mixture includes both the levoamphetamine (l-amphetamine) and dextroamphetamine (d-amphetamine) isomers, with the latter being more potent in producing central nervous system effects.
Inactive Ingredients
In addition to the active ingredients, Adderall contains several inactive ingredients that help form the tablet or capsule and may affect how the medication is absorbed:
Adderall IR Tablets Inactive Ingredients:
- Lactose monohydrate
- Microcrystalline cellulose
- Corn starch
- Colloidal silicon dioxide
- Magnesium stearate
- FD&C Blue #1 (5mg and 10mg tablets)
- FD&C Yellow #6 (20mg and 30mg tablets)
Adderall XR Capsules Inactive Ingredients:
- Gelatin capsules
- Methylcellulose
- Talc
- Triethyl citrate
- Various colorants depending on dosage strength
Note: Individuals with specific allergies or sensitivities should review the complete list of inactive ingredients with their healthcare provider or pharmacist. Those with lactose intolerance should be aware that Adderall IR tablets contain lactose monohydrate.
Safe Dosage Guidelines for Adderall

Adderall dosage must be carefully determined by a healthcare provider based on the individual’s age, condition being treated, response to the medication, and other factors. The following guidelines represent FDA-approved dosages, but individual treatment plans may vary.
Important: Never adjust your Adderall dosage without consulting your healthcare provider. Taking more than prescribed can lead to serious side effects, dependence, or overdose. Taking less than prescribed may result in inadequate symptom control.
Dosage for ADHD (Attention Deficit Hyperactivity Disorder)
Adderall IR (Immediate-Release) Tablets for ADHD:
Age Group | Starting Dosage | Dosage Adjustments | Maximum Daily Dosage | Frequency |
Adults (18+ years) | 5mg once or twice daily | May increase by 5mg weekly | 40mg | 1-3 times daily |
Children (6-17 years) | 5mg once or twice daily | May increase by 5mg weekly | 30mg | 1-3 times daily |
Children (3-5 years) | 2.5mg once daily | May increase by 2.5mg weekly | 40mg | 1-3 times daily |
Adderall XR (Extended-Release) Capsules for ADHD:
Age Group | Starting Dosage | Dosage Adjustments | Maximum Daily Dosage | Frequency |
Adults (18+ years) | 20mg once daily | May adjust weekly as needed | 60mg | Once daily in the morning |
Children (13-17 years) | 10mg once daily | May increase to 20mg after first week | 30mg | Once daily in the morning |
Children (6-12 years) | 5mg or 10mg once daily | May increase by 5mg or 10mg weekly | 30mg | Once daily in the morning |
Dosage for Narcolepsy
Adderall IR tablets are also approved for treating narcolepsy, while Adderall XR is not specifically approved for this condition.
Age Group | Starting Dosage | Dosage Adjustments | Maximum Daily Dosage | Frequency |
Adults (18+ years) | 10mg daily | May increase by 10mg weekly | 60mg | Divided into 2-3 doses |
Children (12-17 years) | 10mg daily | May increase by 10mg weekly | 60mg | Divided into 2-3 doses |
Children (6-11 years) | 5mg daily | May increase by 5mg weekly | 60mg | Divided into 2-3 doses |
Special Dosing Considerations
- First-time users: Often start at the lowest possible dose to assess tolerance and response
- Elderly patients: May require lower doses due to potential increased sensitivity to side effects
- Patients with kidney or liver impairment: May require dosage adjustments
- Timing of doses: First dose typically taken upon waking; additional doses (for IR) should be taken at least 4-6 hours apart
- Avoiding late doses: Taking Adderall too late in the day can interfere with sleep
Consult a Healthcare Provider
The dosage information provided is general guidance. Your healthcare provider will determine the right dosage for your specific needs based on your medical history, current health status, and response to treatment.
Adderall Manufacturers

Several pharmaceutical companies manufacture Adderall and its generic equivalents. Understanding who makes your medication can be important, especially if you notice differences when switching between manufacturers.
Brand-Name Adderall Manufacturers
- Takeda Pharmaceuticals (formerly Shire) – Current manufacturer of brand-name Adderall XR
- Teva Pharmaceuticals – Acquired the rights to manufacture brand-name Adderall IR tablets
- Takeda Pharmaceuticals – Manufacturer of Mydayis (triple-bead extended-release mixed amphetamine salts)
Generic Adderall Manufacturers
Several companies produce generic versions of amphetamine salt combinations. Some of the major manufacturers include:
Teva Pharmaceuticals
One of the largest manufacturers of generic Adderall, producing both immediate-release tablets and extended-release capsules.
Sandoz
Manufactures generic amphetamine salt combination products in various strengths and formulations.
Aurobindo Pharma
Produces generic versions of both Adderall IR tablets and Adderall XR capsules.
Mallinckrodt Pharmaceuticals
Manufactures generic amphetamine salt combination products for the U.S. market.
Amneal Pharmaceuticals
Produces generic versions of Adderall in multiple strengths and formulations.
Sun Pharmaceutical
Manufactures generic amphetamine salt combinations for the U.S. market.
Note on Generic Variations: While the FDA requires generic medications to have the same active ingredients and be bioequivalent to their brand-name counterparts, there can be differences in inactive ingredients. Some patients report variations in effectiveness or side effects when switching between different manufacturers’ versions. If you notice changes after switching manufacturers, discuss this with your healthcare provider.
Pharmacy Availability and Access

As a controlled substance, Adderall has specific regulations regarding its prescription and dispensing. Understanding where and how to access this medication can help patients navigate the healthcare system more effectively.
Major Pharmacies That Carry Adderall
Most major pharmacy chains and independent pharmacies in the United States carry Adderall and its generic equivalents. These include:
National Chains
- CVS Pharmacy
- Walgreens
- Rite Aid
- Walmart Pharmacy
- Target Pharmacy (CVS)
- Kroger Pharmacy
Grocery Store Pharmacies
- Publix Pharmacy
- Safeway Pharmacy
- Albertsons Pharmacy
- H-E-B Pharmacy
- Wegmans Pharmacy
- Giant Eagle Pharmacy
Mail-Order Options
- Express Scripts
- OptumRx
- CVS Caremark
- Humana Pharmacy
- Walmart Mail Order
- Costco Mail Order
Prescription Requirements
Because Adderall is classified as a Schedule II controlled substance, there are strict regulations regarding its prescription:
- Requires a written prescription from a licensed healthcare provider
- In some states, electronic prescriptions (e-prescriptions) are mandatory
- Prescriptions cannot include refills – a new prescription is needed each time
- Some states limit the quantity that can be dispensed at one time
- Photo ID is typically required when picking up the prescription
- Some insurance plans require prior authorization
Supply Issues and Shortages

Since October 2022, the FDA has reported ongoing shortages of Adderall and its generic equivalents. These shortages have affected both immediate-release and extended-release formulations and have been attributed to manufacturing delays and increased demand.
Tips for Navigating Shortages:
- Call ahead: Contact pharmacies before visiting to check if they have your prescription in stock
- Be flexible with generics: Be open to different manufacturers’ versions if available
- Work with your healthcare provider: They may be able to prescribe alternative medications if Adderall is unavailable
- Plan ahead: Don’t wait until you’re completely out of medication to request a new prescription
- Check multiple pharmacies: Availability can vary between different pharmacy locations
Alternative Medications During Shortages
If Adderall is unavailable, your healthcare provider might consider prescribing one of these alternatives:
Medication | Class | Available Forms | Notes |
Methylphenidate (Ritalin, Concerta) | Stimulant | IR tablets, ER tablets, ER capsules, liquid, patch | Different mechanism than Adderall but similar effects |
Dexmethylphenidate (Focalin) | Stimulant | IR tablets, ER capsules | More potent form of methylphenidate |
Lisdexamfetamine (Vyvanse) | Stimulant (prodrug) | Capsules, chewable tablets | Converted to dextroamphetamine in the body |
Atomoxetine (Strattera) | Non-stimulant | Capsules | May take several weeks to reach full effectiveness |
Guanfacine (Intuniv) | Non-stimulant | ER tablets | Originally a blood pressure medication |
Clonidine (Kapvay) | Non-stimulant | IR tablets, ER tablets | Also used for high blood pressure |
Check Current Adderall Availability
For the most up-to-date information on Adderall shortages and availability, visit the FDA Drug Shortages database or contact your local pharmacy directly.
Insurance Coverage and Cost Considerations

The cost of Adderall can vary significantly depending on whether you’re purchasing the brand-name or generic version, your insurance coverage, and the pharmacy you use. Understanding these factors can help you manage the financial aspects of your treatment.
Insurance Coverage
Most insurance plans, including Medicare Part D and Medicaid, cover Adderall and its generic equivalents. However, coverage details vary by plan:
- Prior Authorization: Many insurance plans require prior authorization for Adderall, meaning your doctor must provide additional information to justify the prescription
- Quantity Limits: Plans may limit how much medication you can receive at one time
- Step Therapy: Some plans require you to try other medications before covering Adderall
- Formulary Tiers: Generic versions are typically on lower cost tiers than brand-name versions
Price Comparison: Brand vs. Generic
There can be significant price differences between brand-name and generic versions of Adderall:
Medication | Average Retail Price (30-day supply)* | With Typical Insurance | With Discount Programs |
Brand Adderall IR (20mg) | $250-$300 | $30-$60 | $200-$250 |
Generic Adderall IR (20mg) | $50-$90 | $5-$20 | $25-$45 |
Brand Adderall XR (20mg) | $350-$450 | $40-$80 | $280-$350 |
Generic Adderall XR (20mg) | $100-$150 | $10-$30 | $50-$80 |
*Prices are approximate and may vary by location and pharmacy. Updated as of 2023.
Saving on Prescription Costs
If you’re concerned about the cost of Adderall, consider these options:
- Prescription discount cards: Programs like GoodRx, SingleCare, or RxSaver can provide significant discounts
- Pharmacy comparison: Prices can vary substantially between pharmacies
- Manufacturer assistance programs: Some pharmaceutical companies offer patient assistance programs
- Insurance formulary review: Check if your insurance covers specific manufacturers’ generics
- 90-day supplies: Some insurance plans offer discounts for 90-day supplies
Compare Medication Prices
Use prescription discount services to compare Adderall prices at pharmacies near you and potentially save on your medication costs.
Safe Use and Important Precautions

Using Adderall safely requires understanding important precautions, potential side effects, and proper handling of the medication. This information is crucial for patients and caregivers to ensure effective and safe treatment.
Important Safety Precautions
- Medical supervision: Regular check-ups with your healthcare provider are essential to monitor effectiveness and side effects
- Cardiovascular monitoring: Adderall can increase blood pressure and heart rate; regular monitoring is recommended
- Mental health awareness: Report any changes in mood, behavior, or thoughts to your healthcare provider
- Growth monitoring: In children, height and weight should be regularly monitored as Adderall can affect growth
- Substance use history: Those with a history of substance use disorder require careful monitoring
Common Side Effects
Understanding potential side effects can help you recognize when to seek medical attention:
Common Side Effects:
- Decreased appetite
- Dry mouth
- Trouble sleeping
- Headache
- Stomach pain
- Weight loss
- Nervousness
Serious Side Effects (Seek Medical Help):
- Chest pain or palpitations
- Shortness of breath
- Fainting
- Severe headache
- Numbness in extremities
- Seizures
- Hallucinations or paranoia
Drug Interactions
Adderall can interact with numerous medications. Always inform your healthcare provider about all medications, supplements, and herbs you’re taking. Some important interactions include:
- MAO inhibitors: Can cause dangerous increases in blood pressure
- Antidepressants: May increase risk of serotonin syndrome
- Blood pressure medications: Adderall may reduce their effectiveness
- Antacids and acid-reducing medications: Can affect Adderall absorption
- Vitamin C: High doses can reduce Adderall absorption
Proper Storage and Handling
- Store at room temperature (68°F to 77°F or 20°C to 25°C)
- Keep in a tightly closed, light-resistant container
- Store in a secure location away from children and pets
- Do not share your medication with others (illegal and dangerous)
- Properly dispose of unused medication through drug take-back programs
Warning: Adderall is a controlled substance with potential for misuse and dependence. Never take more than prescribed, and never share your medication with others. Misuse can lead to serious health consequences, including cardiovascular problems, psychosis, and legal consequences.
Conclusion: Making Informed Decisions About Adderall
Adderall is an effective medication for managing ADHD and narcolepsy when used as prescribed under proper medical supervision. Understanding the different types, appropriate dosages, ingredients, and availability can help patients and caregivers make informed decisions about treatment.
Remember that Adderall is just one component of a comprehensive treatment approach. For ADHD, behavioral therapy, educational interventions, and lifestyle modifications are also important parts of an effective treatment plan. For narcolepsy, sleep hygiene and other supportive measures may be recommended alongside medication.
Always work closely with your healthcare provider to determine the most appropriate treatment approach for your specific needs, and maintain regular follow-up appointments to monitor effectiveness and address any concerns that may arise during treatment.
Consult a Healthcare Professional
This article provides general information about Adderall and is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for personalized guidance about your specific situation.